Christopher J. Chermansky, M.D.

Education and Training
Undergraduate

1982 - 1986

Saint Vincent College Latrobe, PA

B.S. in 1986 Biology

Graduate

1986 - 1990

Georgetown University School of Medicine Washington, D.C.

M.D. in 1990 Dr. William Maxted Urology

Postgraduate

1990 - 1991

University of Texas Southwestern Medical Center Dallas, TX

Dr. C. James Carrico General Surgery

Residency

1991 - 1996

University of Texas Southwestern Medical Center Dallas, TX

Dr. John D. McConnell Urology

Postdoctoral Fellowship

1999 - 2001

University of California at San Francisco San Francisco, CA

Dr. Emil A. Tanagho Urology

NIH K12 Physician Scientist Fellow in Neurourology and Female Neurology

2001 - 2004

University of Pittsburgh Medical Center Pittsburgh, PA

Dr. Michael B. Chancellor Urology

Appointments and Positions
Academic
Instructor in Urology at the University of Pittsburgh 2002 - 2004

Non-Academic
Military

1996 - 1999

David Grant Medical Center Travis Air Force Base, CA United States Air Force

Major / Staff Urologist

Certification and Licensure
Specialty Certification
Successful Completion of Part I of the American Board of Urology Certification Exam in June 1996

Medical or Other Professional Licensure
Medical Board of California - A76588 (2001 - Present)
Pennsylvania State Board of Medicine - MD4I 8680 (2003 - Present)

Memberships in Professional and Scientific Societies
American Urological Association (AUA) (1996 - Present)
Western Section of AUA (2000 - 2001)
Pennsyivarua Medical Society (2002 - Present)
Allegheny County Medical Society (2002 - Present)
Northeastern Section of AUA (2003 - Present)
Pittsburgh Urological Association (2003 - Present)

Honors
United States Air Force Health Professions Scholarship (1986)
NIH/K12 Physician Scientist Fellowship in Neurourology and Female Urology

Publications
Refereed Articles
Cayan, S., Chermansky, C,, Schlote, N., Sekido, N. Nunes, L., Dahiya, R., and Tanagho, B.: The Bladder Acellular Matrix Graft in a Rat Chemical Cystitis Model: Functional and Histologic Evaluation, J. Urol., 168:798-804, 3002.

Lu, S., Cannon T.W., Chermansky, C., Pruchnic, R., Somogyi, G., Sacks, M., de Groat, W.C., Huard, J., and Chancellor, MB.: Muscle-Derived Stem Cells Seeded into Acellular Scaffolds Develop Calcium-Dependent Contractile Activity that is Modulated by Nicotinic Receptors. Urology, 61:1285-1291, 2003.

Chermansky, C.J., Tarin, T., Kwon, D., Jankowski, R.J., Cannon, T.W., de Groat, W.C., Huard, and Chancellor, M.R: Tnttauretlnal Muscle Derived Cell Injections increase Leak Point Pressure in a Rat Model of Intrinsic Sphincreric Deficiency. Urology, 63:780-785, 2004.

Chermansky, C.J., Cannon, T,W., Torimoto, K., Fraser, MO., Yoshimura, N., de Groat, W.C., and Chancellor, MB.: A Model of Intrinsic Sphincteric Deficiency in the Rat: Electrocauterization. Neurourology and Urodynamics, 23:166-171, 2004.

Reviews, invited published papers proceedings of conference and symposia, monographs, books and book chapters
Chermansky, C.J. and Chancellor, M.B.: Increasing Awareness and Improving the Care of Urinary Incontinence: Highlights from the World Health Organization 2nd International Consultation on Incontinence July 1-4, 2001, Paris, France, Reviews in Urology, 5:22-25, 2003.

Chermansky, C.J., Huard, J., and Chancellor, MB.: Gene Therapy Using Muscle Derived Stem Cells, in Adult Stem Cells (Turksen, K., ed.), The Humana Press Inc., Totowa, N.J. 51-66, 2004.

Chermansky, C.J. and Chancellor, M.D.: Transdermal Oxybutynin in the Treatment of Overactive Bladder. Today's Therapeutic Trends, 21, 295-306, 2003.

Chermansky, C.J. and Chancellor, MB.: Estrogen for Overactive Bladder and Patient Perception of Incontinence. Reviews in Urology, 6:94-95, 2004.

Published Abstracts
Richier, J.C., Kaplan, EP., Chermansky, C,J., Ewalt, D.H., Lin, V.K,, and McConnell, J.D.: Analysis of Type III Collagen mRNA Expression in Human Benign Prostaric Hyperplasia. J. Urol, 153:344A, 1995.

Cayan. S., Chermansky, C,, Schlote, N., Sekido, N., Nunes, L., Dahiya, R., and Tanagho, B.: The Bladder Acellular Matrix Graft in a Rat Chemical Cystitis Model: Functional and Histologic Evaluation. J. Urol., 167:9, 2002.

Lu, S.H., Chung, S., Sellaro, T., Gloeckner, D., Sacks, M., Huard, J., deGroat, W., Chermansky, C. and Chancellor, M.: Could Muscle-Derived Stem Cells make Small Intestinal Submucosa more Compliant for Bladder Reconstitution? J. Urol., 167:58, 2002.

Chermansky, C., Lu, S.H., de Groat, W.C., Sornogyi, G., Huard, J., Pruchnic, R., and Chancellor, ME.: Contractility of Small Intestinal Submucosa and Muscle-Derived Stem Cells. J. Spinal Cord Med., 25:234, 2002.

Chermansky, C., Lu, S.H., Chung, S., Sellaro, T., Gloeckner, D.C., Huard, J., de Groat, W.C., and Chancellor, MB.: Muscle-Derived Stem Cells Improve Bladder Compliance for Small Intestinal Submucosa. J. Spinal Cord Med., 25:234, 2002.

Pruchnic, RJ., Huard, J., Chermansky, C., Yoshimura, N., deGroat, W.C., and Chancellor, M.D.: Human Skeletal Muscle-Derived Stem Cells for Improving Neurogenic Bladders. J. Spinal Cord Med., 25:242 2002.

Youssif, ME., Shiina, H.., Shirai, M., Nunes, L., Gleason, C., Chermansky, C., Igawa, M., Dahiya, R., and Tanagho, E.A.: Regeneration of the Bladder Acellular Matrix Graft in a Diabetic Rat Model, J. Urol., 169:41, 2002.

Tarin. TV., Chermansky, C.J., Kwon, D.D., Cannon, T., Huard, J., and Chancellor, M.B.: Periurethral Muscle Derived Stem Cell Injections Increase Leak Point Pressure in a Rat Model of Intrinsic Sphincreric Deficiency. J. Urol., 169:96, 2003.

Lu, S.U., Cannon, T.W., Chermansky, C., Pruchnic, R., Somogyi, G., Sacks, M., de Groat, W.C., Huard, J., and Chancellor, MB.: Muscle-Derived Stem Cells Seeded Acellular Scaffolds Improves Compliance and Develop Calcium Dependent Contractile Activity that is Modulated by Nicotinic Receptors. J. Urol., 169:102, 2003.

Kim, J.H., Bennett, N., Yoshimura, N., Cherxnansky, C., Kwon, D.D., Tarin, T., Nelson, SB,, de Groat, W.C., Qu-Peterson, Z., Huard, J., and Chancellor, MD,; Neurorecovery and Improved Erectile Function Using Muscle Derived Stem Cells (MDSC) in a Model of Post-Radical Prostatectomy Erectile Dysfunction. J. Urol. 169:323, 2003.

Cannon, T.W., Conway, D., Lu, S.H., Xavier, M., Fraser, MO., Chermansky, C., de Groat, W.C., Huard, J., and Chancellor, MB.: Leak Point Pressure Testing After Tissue Engineered Sling Placement in a Model of Stress Urinary Incontinence. J. Urol., 169:350, 2003.

Chancellor, MB., O'Leary, MO., Erickson, J., Cannon, T.W. Chermansky, C., Leng, W.W., Smith, C.P.: Successful Use of Bladder Botulinum Toxin Injection to Treat Refractory Overactive Bladder. J. Urol., 169:351, 2003.

Cannon, T.W., Xavier, M,, O'Leary, MO., Chermansky, C., Erickson, J., Leng, W., and Chancellor, MB.: Correlation of Bladder and Sexual Function in Women with Neurological Disabilities. J. Urol., 169:374 2003.

Cannon T., Conway D., Lu, S.H., Xavier M., Fraser MO., Chermansky, C., de Groat, W., Huard, J., and Chancellor, M.: Leak Point Pressure Testing after Tissue Engineered Sling Placement in a Model of Stress~ess Urinary Incontinence. Neurouro Urodyn., 22:372, 2003.

Chermansky, C., Tarin, T, Kwon, D., Cannon, T., de Groat, W., Huard, J., and Chancellor, M.: Intraurethral Muscle Derived Cell Injections Increase Leak Point Pressure in a Rat Model of Intrinsic Sphincteric Deficiency. Neurouro Urodyn., 22:389-390, 2003.

Professional Activities
Appointments Attending Physician, David Grant Medical Center, Travis AFB, CA, 1996-1999.

Clinical Instructor, Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 2002-2004.

Peer Reviewer
Journal of Spinal Cord Medicine (2003 - Present)

Speaker
Pfizer Phatmaceuticals (2003 - Present)

Teaching Invited Speaker, "Medical Management of BPH", Westmoreland Hospital Grand Rounds, Greensburg, PA, January 1996.

Invited Speaker, "Medical Management of BPH", Family Practice Staff and Residents, David Grant Medical Center, Travis AFB, CA, November 1996.

Invited Faculty, "Impotence", David Grant Medical Center Outpatient Medicine Symposium, Lake Tahoe, CA, January 1997

Invited Speaker, "Treatment Options for Localized Psostate Cancer", Family Practice Staff and Residents, David Grant Medical Center, Travis AFB, CA, April 1997.

Invited Speaker, "Preventative Management of Kidney Stone Disease", Family Practice Staff and Residents, David Grant Medical Center, Travis AFB, CA, September 1997.

Invited Speaker, "Medical Management of BPH", Internal Medicine Staff and Residents, David Grant Medical Center, Travis AFB, CA, October 1997.

Invited Faculty, "Use of Intestinal Segments and Urinary Diversion", Nursing Enterostomal Care, David Grant Medical Center, Travis AFB, CA, December 1997.

Invited Speaker, "Treatment Options for Metastatic Prostate Cancer", Internal Medicine Staff and Residents, David Grant Medical Center, Travis AFB, CA, February 1998.

Invited Speaker, "Female Stress Urinary Incontinence", Internal Medicine Staff and Residents, David Grant Medical Center, Travis AFB, CA, August 1998.

Invited Faculty, "Use of Intestinal Segments and Urinary Diversion", Nursing Enterosroinal Care, David Grant Medical Center, Travis AFB, CA, September 1998.

Invited Speaker, "The Bladder Acellular Matrix Graft: Past and Future Directions", Dr. William deGroat's Research Meeting, Pittsburgh, PA, February 2002.

Invited Faculty, "Urinary Tract Infections". University of Pittsburgh 3rd Year Medical Student Surgical Specialties Clerkship, Pittsburgh, PA, November 2002.

Invited Faculty, "Voiding Dysfunction", University of Pittshurgh 3rd Year Medical Student Surgical Specialties Clerkship, Pittsburgh, PA, November 2002.

Invited Faculty, "Voiding Dysfunction", University of Pittsburgh 3rd Year Medical Student Surgical Specialties Clerkship, Pittsburgh, PA, December 2002.

Invited Faculty, "Voiding Dysfunction", University of Pittsburgh 3rd Year Medical Student Surgical Specialties Clerkship, Pittsburgh, PA, January 2003.

Invited Speaker, "Periurethral MDSC Injections Increase LPP in ISD Rats", Dr. William deGroat's Research Meeting, Pittsburgh, PA, January 2003.

Invited Faculty, "Voiding Dysfunction", University of Pittsburgh 3rd Year Medical Student Surgical Specialties Clerkship, Pittsburgh, PA, Pebruary 2003.

Invited Faculty, "Interstitial Cystitis", Department of Urology Residents Journal Club, Pittsburgh, PA, March 2003.

Invited Speaker, "The Periurethral Injection of MDC Increase LPP in ISD Rats", Dr. Johnny Huard's Research Meeting, Pittsburgh, PA, March 2003.

Invited Speaker, "The Periurethral Injection of MDC Increase LPP in ISD Rats", Engineering Tissue Growth International Conference and Exposition Meeting, Pittsburgh, PA, March 2003.

invited Speaker, "BPH and Tips on Difficult Catheterizations", UPMC Rehabilitation Hospital Nursing Inservice, Pittsburgh, PA, March 2003.

Invited Speaker, "BPH and Prostate CA Screening", University of Pittsburgh School of Nursing Lecture for Nurse Practitioner Students, Pittsburgh, PA, March 2003.

Invited Faculty, "Postprostatectomy Incontinence", University of Pittsburgh Department of Urology Grand Rounds, Pittsburgh, PA, April 2003.

Invited Speaker, "Incontinence after Prostate Surgery", Lecture to US TOO Prostate Cancer Support Group, Pittsburgh, PA, May 2003.

Invited Faculty, "Stress Urinary Incontinence", Department of Urology Residents Journal Club, Pittsburgh, PA, December 2003.

Invited Speaker, "BPH and Prostate CA Screening", University of Pittsburgh School of Nursing Lecture for Nurse Practitioner Students, Pittsburgh, PA, February 2004.

Invited Faculty, "Male Chronic Pelvic Pain Syndrome", University of Pittsburgh Department of Urology Grand Rounds, Pittsburgh, PA, June 2004.

List of Current Research Interest
Muscle Derived Stem Cell Mediated Gene Therapy for Incontinence (ROI-DK55387-01)

Role of Peripheral and Spinal Endothelin Mechanisms in the Micturition Reflex of Rats with Cystitis and Detrusor Overactivity

Past Research
NIH Sponsored Grant: RO1-DK51101-05, Regeneration of Functional Smooth Muscle Tissue in the Bladder Acellular Matrix Graft, Co-investigator, 10% effort, 2000-2005.

Seminars and invited lectureships related to research: Invited Presenter, "The Bladder Acellular Matrix Graft in a Rat Chemical Cystitis Model: Functional and Histologic Evaluation", International Bladder Symposium. Washington, D.C., March 2001.

Service
Committees and Academic Services

• Pharmacy and Therapeutics Committee, David Grant Medical Center, Travis AEB, CA, 1996-1998.
• Tissue Review Committee, David Grant Medical Center, Travis AFB, CA, 1996-1998.

• Berkeley Free Clinic, Berkeley, CA, 1999-2001.
• Prostate Health for UPMC Bladder health Symposium, Pittsburgh, PA, June 11, 2002.
• Male Erectile Dysfunction and Treatments for Sex (and MS) in the City, Pittsburgh PA, October 7, 2002.